Chelsea will begin the defence of their Premier League title with a home match against newly promoted West Bromwich Albion on Saturday 14 August.
Heavyweights Liverpool and Arsenal will meet at Anfield on the opening weekend.
Last season's runners-up Manchester United face a mouth-watering home match with top-flight new boys Newcastle.
Championship play-off winners Blackpool start at home to Wigan, while Tottenham host Manchester City, who they edged out for fourth place last term.
Elsewhere on the opening day of the 2010/11 season, Aston Villa face West Ham and Everton travel to Blackburn, while Steve Bruce's Sunderland are at home to his old club Birmingham, Stoke visit Wolves and Bolton welcome Europa League runners-up Fulham.
Chelsea will come up against one of their former players in Baggies manager Roberto Di Matteo in their opener.
Next up for the champions will be a trip to Wigan, where they were beaten last season, before Stoke visit Stamford Bridge on 28 August.
Carlo Ancelotti's title holders have to wait until 2 October for their first match against one of last season's top four clubs, when they face Arsenal at home, with the return fixture on Boxing Day.
Chelsea host Manchester United on 18 December, with the two coming together at at Old Trafford on 7 May - the penultimate away fixture for the Blues.
Ian Holloway's Blackpool will know all about the rigours of the top flight by the time they travel to Old Trafford - the visit comes on the final day, giving them a tough end to the campaign on 22 May.
Opening weekend -
Saturday, 14 August
Aston Villa v West Ham
Blackburn v Everton
Blackpool v Wigan
Bolton v Fulham
Chelsea v West Brom
Liverpool v Arsenal
Man Utd v Newcastle
Sunderland v Birmingham
Tottenham v Man City
Wolverhampton v Stoke
Saturday, 21 August
Arsenal v Blackpool
Birmingham v Blackburn
Everton v Wolverhampton
Fulham v Man Utd
Man City v Liverpool
Newcastle v Aston Villa
Stoke v Tottenham
West Brom v Sunderland
West Ham v Bolton
Wigan v Chelsea
Saturday, 28 August
Aston Villa v Everton
Blackburn v Arsenal
Blackpool v Fulham
Bolton v Birmingham
Chelsea v Stoke
Liverpool v West Brom
Man Utd v West Ham
Sunderland v Man City
Tottenham v Wigan
Wolverhampton v Newcastle
Heavyweights Liverpool and Arsenal will meet at Anfield on the opening weekend.
Last season's runners-up Manchester United face a mouth-watering home match with top-flight new boys Newcastle.
Championship play-off winners Blackpool start at home to Wigan, while Tottenham host Manchester City, who they edged out for fourth place last term.
Elsewhere on the opening day of the 2010/11 season, Aston Villa face West Ham and Everton travel to Blackburn, while Steve Bruce's Sunderland are at home to his old club Birmingham, Stoke visit Wolves and Bolton welcome Europa League runners-up Fulham.
Chelsea will come up against one of their former players in Baggies manager Roberto Di Matteo in their opener.
Next up for the champions will be a trip to Wigan, where they were beaten last season, before Stoke visit Stamford Bridge on 28 August.
Carlo Ancelotti's title holders have to wait until 2 October for their first match against one of last season's top four clubs, when they face Arsenal at home, with the return fixture on Boxing Day.
Chelsea host Manchester United on 18 December, with the two coming together at at Old Trafford on 7 May - the penultimate away fixture for the Blues.
Ian Holloway's Blackpool will know all about the rigours of the top flight by the time they travel to Old Trafford - the visit comes on the final day, giving them a tough end to the campaign on 22 May.
Opening weekend -
Saturday, 14 August
Aston Villa v West Ham
Blackburn v Everton
Blackpool v Wigan
Bolton v Fulham
Chelsea v West Brom
Liverpool v Arsenal
Man Utd v Newcastle
Sunderland v Birmingham
Tottenham v Man City
Wolverhampton v Stoke
Saturday, 21 August
Arsenal v Blackpool
Birmingham v Blackburn
Everton v Wolverhampton
Fulham v Man Utd
Man City v Liverpool
Newcastle v Aston Villa
Stoke v Tottenham
West Brom v Sunderland
West Ham v Bolton
Wigan v Chelsea
Saturday, 28 August
Aston Villa v Everton
Blackburn v Arsenal
Blackpool v Fulham
Bolton v Birmingham
Chelsea v Stoke
Liverpool v West Brom
Man Utd v West Ham
Sunderland v Man City
Tottenham v Wigan
Wolverhampton v Newcastle
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